look at the model below representing a signal transduction in a cell: a model of signal transduction. ions are outside of the cell. a signal molecule has bonded to the surface protein, and the protein gate is open. ions are free to enter the cell. which of the following would not necessarily stimulate a cellular response? a bonded signal molecule and surface substrate a large concentration of hormones outside of the cell a large concentration of ions inside of the cell an open gate for the specific ions