Consider two solutions separated by a semipermeable membrane, as shown in the illustration to the right. The membrane allows the passage of small molecules and ions, but not large molecules like polysaccharides or proteins. Solution A contains a 10% solution composed
of glucose and the protein albumin dissolved in water.
Solution B contains a 5% solution of NaCl in water. Indicate whether each substance in the system would flow into Solution A, Solution B, or neither.

1. Water
2. NaCl
3. glucose
4. Albumin
5. Glucose

All the substances are separated by the semipermeable membrane and the semipermeable membrane allows the only small molecule to pass through it. So the movement of the given substance would be -

1. Water - into solution A.

Water molecules are small and can easily pass through the semipermeable membrane as it is given that the solution b has low solute concentration and solution A has high solute concentration. It is known that the movement of the solvent always takes place from low solute concentration to high so the movement of water will be into solution A.

2. NaCl - into solution A.

The movement of small ionic molecule NaCl is always from high to low concentration as it is given that solution B has high concentration than solution A so movement will take place into solution A.

3. glucose - into Solution B.

It is also a small molecule and moves from the high glucose region to the low glucose concentration region, in solution A the concentration of glucose is high than solution B so movement would be into solution B.

4. Albumin - neither.

Albumin is a protein which is macromolecule and large in size to pass through the semipermeable membrane so, albumin move neither solution A nor solution B.