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Select the statement that best explains why the replication machinery is found at the replication fork. Multiple Choice The replication machinery can move fastest orid most efficiently along the DNA template at the replication fork. The replication machinery must be able to open and stabilize the template DNA and it must have access to both template strands for replication The replication fork is a specific sequence of DNA to which the replication machinery is permanently bound The replication machinery can move fastest and most efficiently along the DNA template at the replication fork The replication machinery must be able to open and stabilize the template DNA, and it must have access to both template strands for replication The replication fork is a specific sequence of DNA to which the replication machinery is permanently bound The replication fork is the region of DNA that is capable of initially being nicked and opened up by the replication machinery so the replication machinery stays at this spot in order to replicate the DNA

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The replication machinery must be able to open and stabilize the template DNA and it must have access to both template strands for replication. Option B.

Replication is very rapid because multiple polymerases can synthesize two new strands simultaneously, using each unwound strand of the original DNA duplex as a template. Replication is initiated by a virus-encoded protein that binds to the origin and also functions as a helicase.

A single-stranded DNA binding protein is required to stabilize the unwound template and the DNA polymerase-α-primase complex initiates DNA synthesis. The replication machinery, the replisome complex consists of a number of specialized proteins that function to support replication by DNA polymerases.

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