Physical features of patients with cushing syndrome are: Round face or moon face Weight gain with excess body fat Cervical fat pad, capillary friability, thin skin with purple striae Decreased muscle mass Glucose intolerance, hyperglycemia, hypertension Demineralization of bone Increased androgen production
Cushing syndrome is a disease which is caused by excess in cortisol secretion and does not depend on stimulation from ACTH. The most common cause is a noncancerous tumor of the adrenal gland, adrenal adenoma,.